Reactions and synthesis – Page 12
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ResearchMethod to make unusual oligonucleotides could be a boon for gene therapy drugs
Synthesis can insert unusual linkages into DNA molecules while rivalling industry standard chemistry in speed and efficiency
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ResearchGiant molecular cage protects plastic-eating enzyme
Caged protein withstands temperatures much hotter than its usual melting point and becomes 1000 times more resistant to solvents
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ResearchEnantioselective synthesis of elusive chiral nitrogen compounds discovered by chance
An ‘elegant and simple’ way to make nitrogen stereocentres by supramolecular recognition
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ResearchWater splitting electrocatalyst made from unconventional alloy containing 14 elements
Simple dealloying process creates complex nanoporous alloy
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ResearchElectrons in zinc’s filled 3d orbitals can participate in chemical reactions
Super electrophilic trianions accept three additional electrons to support zinc in a +3 oxidation state
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ResearchBlue light squeezes out heteroatoms from small rings
Photochemical ring editing reaction allows complete molecular shape change in a single step
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ResearchNo more worrying about nomenclature – AI will tell you what that chemical is called
Open-source online resource converts organic chemical structures to their Iupac names and vice versa
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ResearchApp creates floating 3D molecules from hand-drawn chemical structures
MolAR also lets users visualise molecules in water, coffee and fruit by scanning them with a smartphone camera
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ResearchGold(III) catalysis transforms protecting group from base-stable to base-labile
Unique orthogonality in a protecting group achieved using a gold-catalysed cyclisation for selective activation and deprotection
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ResearchMolecular cryo-EM discovers error in 25-year-old natural product structure
Nobel prize-winning biomolecule imaging technique adapted to characterise chemical compounds faster and easier than NMR and x-ray
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ResearchPhotocatalyst couples denitrification and water splitting to manage nitrate pollution
Hydrogen gas generated in situ serves as reducing agent
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ResearchMirror image enzyme constructs longest ever mirror DNA strand
Since chirally inverted DNA is more stable than its natural counterpart, it can be used to encode secret messages
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ResearchHeavy-atom quantum tunnelling catalysed with Lewis acids
Lewis acid–base interactions found to increase quantum tunnelling rates of rearrangement reaction
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ResearchSafer fluorination process developed using flow electrochemistry
Automated system for constructing carbon–fluorine bonds quenches fluorine compounds to reduce exposure and risk to lab chemists
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![An image showing a [M2(BzN6-Mes)]n− complex](https://d2cbg94ubxgsnp.cloudfront.net/Pictures/100x67/4/0/8/514408_index_128835.jpg)
ResearchMetal sandwich stabilises first benzene triplet-state aromatic
Benzene diradical dianion is the first monocyclic molecule that’s Baird aromatic in the ground state
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ResearchTransient spectroscopy sheds light on elusive photoredox process
Study confirms mechanism of sensitisation-initiated electron transfer reaction following extended debate
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ResearchElectrocatalysis offers green alternative for ethylene purification
Copper catalysts enable selective and efficient acetylene reduction at ambient conditions
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ResearchNewly discovered marine compound is in a super-carbon-chain league of its own
Isolated from algae, Benthol A has 35 stereocentres
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ResearchMolecular light switch speeds up tricky cyclodextrin synthesis
Reaction could lower cost of useful macrocycle
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ResearchAluminium compound deconstructs sulfur hexafluoride in minutes
Method turns potent greenhouse gas into useful synthetic reagents