Reactions and synthesis – Page 27
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ResearchBlood pressure drug reacts with membrane lipids
Lipidation products add to evidence that biological membranes are far from chemically inert
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ResearchNew tools direct reactions at specific C–H bonds in organic molecules
Elegant catalysts offer quicker routes to complex compounds
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ResearchCatalytically, is copper the new gold?
Approach for depositing copper on silica support influences how easily it oxidises, and in turn the reactions it catalyses
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ResearchNanoparticles assemble into first single-ingredient quasicrystal
Predicted a decade ago, the first one-component quasicrystal has been made from tetrahedral particles
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ResearchDispute over reaction prediction puts machine learning’s pitfalls in spotlight
Two research teams’ argument over a reaction-predicting algorithm show that there is still a lot to understand when applying machine learning to chemistry
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ResearchFoam catalyst performs hydrogen evolution in neutral conditions
Structure decouples water dissociation and hydrogen evolution processes
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ResearchLight catalyst breaks mirror symmetry in first reverse racemisation
Transformation makes single mirror image molecules in a ‘completely different way of doing enantioselective chemistry’
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ResearchCatalyst predictor shows drug manufacturing promise
Joint industrial–academic team develops and validates force-field tool for identifying ligands for enantioselective catalysis
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ResearchDwarf planet Ceres turns out to be extra-carbony
Asteroid belt’s largest object, thought to be a piece of rock, contains up to 20% carbon
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ResearchWeird mechanism behind catnip compound’s biosynthesis uncovered
Nepetalactone – the compound cats go crazy for – is made by a two-step procedure that is unlike any other in terpenoid biosynthesis
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ResearchCrop rotation for catalysts
Chemists take a leaf out of agriculture books to devise method for extending catalyst lifetime
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ResearchDouble umpolung approach to amino amide synthesis
Unusual disconnection strategy behind stereocontrolled route to β-amino amides
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ResearchWorld record for longest carbon–carbon bond broken
Carborane bond surpasses previous longest bond after just nine months in the top spot
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ResearchErythropoietin benefits from controlled sugar-coating
Click chemistry allows glycosylation at virtually any synthetic stage
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ResearchRobotic organic synthesis to make reproducibility simple in chemistry
Chemputer claims universality after making three drugs without human intervention
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ResearchComputation trick cuts total synthesis from 27 to nine steps
Quantum mechanical modelling shows speedy route to terpene natural product
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ResearchMolecular decoration determines origin of MOF acidity
Analytical combo used to pinpoint strong Brønsted acid site in promising next-generation solid acid catalyst
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ResearchPhosphorus beats palladium in connecting nitrogen rings
An entirely metal-free reaction goes where no traditional cross-coupling has gone before – to link pyridines
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ResearchCatalytic fix for nitrogen fixation
Single-atom ruthenium catalyst doubles efficiency of electrochemical reduction of nitrogen to ammonia
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ResearchCocrystal intermediate is first for mechanochemistry
In situ Raman spectroscopy reveals how reactants align prior to forming new bond