Organic chemistry
The latest chemistry news and research on organic chemistry, including synthesis, natural products and total synthesis, reaction mechanisms and supramolecular chemistry, from the Royal Society of Chemistry's magazine, Chemistry World
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ResearchA current take on the Swern oxidation
Electrochemical update to a classic reaction trades cryogenic conditions for room temperature, to selectively convert primary and secondary alcohols into aldehydes and ketones
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NewsUK’s new national laboratories site will support ‘invisible infrastructure’ of measurements that keep world in sync
£20 million investment by LGC will boost country’s analytical and metrology capabilities
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Opinion(−)-Novofumigatonin
Oxidations abound in this satisfying synthesis, with a delicate nitrile hydrolysis to finish
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ResearchQuantum tunnelling drives aromaticity flip-flop
Augmented pentalene structure could be a molecular Schrödinger’s cat, aromatic and antiaromatic at the same time
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ResearchThis fragment-based drug discovery library is designed to be sociable
Study targets a key bottleneck in hit to lead optimisation by designing fragments that are both structurally diverse and easy to elaborate
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ResearchAll stirred up: chemical engineers refute claims that ‘stirring doesn’t matter’
Failing to mix reactions in heterogeneous or industrial systems could cause numerous issues and might even be dangerous, preprint claims
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ResearchDihydropyrazine-embedded macrocycles behave like supersized cycloalkanes
Giant molecular rings that mimic the puckered shapes of cyclobutane, cyclopentane and cyclohexane could offer new insights into conformational dynamics
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Research‘Stimulating discovery’ leads to strategy to swap oxygen in saturated rings
Skeletal editing pushed beyond aromatic structures, sparking new opportunities in drug discovery
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OpinionMy arcane and curious connection to metal-organic frameworks
Fernando Gomollón-Bel uncovers a link between his hometown and the 2025 Nobel prize in chemistry
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NewsMeet the three scientists who have just won the Nobel prize in chemistry
Learn about the lives of newly minted chemistry Nobel laureates Susumu Kitagawa, Richard Robson and Omar Yaghi
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NewsExplainer: why have metal–organic frameworks won the Nobel prize in chemistry?
Susumu Kitagawa, Richard Robson and Omar Yaghi scooped the Nobel prize for their work on MOFs – here’s everything you need to know
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News2025 chemistry Nobel prize goes to the scientists behind metal–organic frameworks
Susumu Kitagawa, Richard Robson and Omar Yaghi take top prize for discovery and development of versatile materials with a huge surface area
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NewsThe 2025 Nobel prize in chemistry as it happens – live
Join us as we provide analysis and commentary in the run up to the announcement of the biggest prize in chemistry
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Webinar200 years of benzene, the peculiar molecule that defied classification
Join us on 11 November to celebrate benzene’s 200th birthday
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OpinionBuilding better batteries with chemistry’s toolbox
How organic chemistry powers the development of sustainable batteries
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ResearchOne-pot atom swap chemistry allows direct indole-to-benzimidazole conversion
Industrial chemists set to benefit from addition to skeletal editing toolbox
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ResearchComprehensive investigation suggests stirrer bars have little impact on reactions
Examination of over 300 organic reactions suggests stirring is nothing more than a placebo
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ResearchPorphyrin ring pushes the size limit for fully aromatic molecules
Nanoring structure features 18 porphyrin units linked together by butadiyne units
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ResearchReviving organobismuth chemistry
Despite its low cost and low toxicity, bismuth has found limited applications in organic synthesis. Liam Ball is working to change that
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WebinarExploring the frontiers of the periodic table: bismuth catalysis and its applications
Learn about state-of-the-art synthesis coming from one of the world’s leading catalysis research groups