Organic chemistry – Page 40
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ResearchAcene synthesis sets new record for twisted molecules
Chemists prepare ‘twistacenes’ with torsion angles of up to 170º
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ResearchWhat’s left isn’t always right in total synthesis
Scientists turn detective to solve a decade-old stereochemical enigma
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ResearchTagging drugs with heavy hydrogen made as easy as flicking a light switch
Photoredox reaction simplifies metabolism studies by swapping hydrogen for deuterium or tritium
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OpinionThe value of quantification
A skills gap is emerging in organic synthesis that needs to be closed
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ResearchSpaces can be useful
Truly functional MOFs are on the horizon but Susumu Kitagawa saw their potential when they were weak and idle
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OpinionNatural selection
Bioactive compounds don’t just inspire new synthetic strategies, they’re also the ultimate test
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Opinion(‒)-Pavidolide B
An innovative approach to making five-membered carbon rings makes for a strikingly short synthesis
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ResearchFlash lithiation made safe
Micromixing enables protecting-group-free synthesis of organolithiums
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WebinarWho says there are no shortcuts to great chemistry?
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ResearchPurple crystals boast first aluminium double bond
Aluminium analogue of an alkene completes series of double-bonded boron group elements
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ResearchHelicene twists aromaticity to its limit
Six-pronged molecule contains the most twisted and least aromatic benzene ring found yet
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ResearchRoute to fiendishly complex marine molecule cut in half
Shortcut to promising natural product already in Alzheimer’s and HIV trials
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ResearchReductive power of hydrated electrons unleashed with green lasers
New technique produces solvated electrons with a visible-light responsive photocatalyst
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ReviewOrganic chemistry: a very short introduction
A beginner’s guide to one of the most exciting areas of modern science
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FeaturePhotoredox: charge of the LED brigade
Forget fluorescent light bulbs, photochemistry has become a lot more sophisticated
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OpinionForcing fluorines into shape
Sometimes unnatural molecules can be more challenging to synthesise than natural metabolites
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ResearchSuper-electrophilic ions enable selective modification of bioactive molecules
New technique will help medicinal chemists explore chemical space
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OpinionAn opportunity ignored
Dismissing ideas that were ‘not invented here’ is like walking past a $100 bill