Organic chemistry – Page 42
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OpinionMake room for randomness in drug development
Setting free the dark horses sometimes beats the most rational planning
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WebinarCurrent topics in bioconjugation
Insights into making bioconjugates using optimal reagents and the latest techniques to create highly active and stable complexes
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ResearchElectric shock brings diamines to life
A combination of electrochemistry and organic catalysis transforms alkenes into hard-to-make vicinal diamines
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FeatureHofmann's chemistry factory
How two German chemists shaped chemistry education and research in Britain
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ResearchStructural sleuthing salvages superbug slayer
Combining ‘assembly line’ synthesis, spectroscopy and computational predictions solves stereochemistry riddle
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PodcastPiranha solution
When you need to get your glassware extremely clean, you need a cleaning solution with real ‘bite’
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![Top view of the single-crystal X-ray diffraction structure of a dithienothiophene (DTT)-bridged [34]octaphyrin](https://d2cbg94ubxgsnp.cloudfront.net/Pictures/100x67/3/6/2/132362_Bicyclic-Baird-type-aromaticity-fig-1-c.jpg)
ResearchUnusual bicyclic molecule extends frontier of aromaticity
Odd resonance stabilisation observed in ground state opens door to studying poorly understood phenomenon
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Opinion(+)-Pleuromutilin
Total synthesis is sometimes the only way to explore the chemical space around a natural product
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ResearchAutomated exploration of chemical space finds two new reactions
Synthetic chemists hit on undiscovered reactions by processing data from a high throughput screen of tens of thousands of potential products
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ResearchPolar solvents promote halogen bonds over hydrogen ones
Solvent decides bonding battle winner in supramolecular systems
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OpinionNickel catalyst couples alcohols and carbon dioxide
Flexibility and low cost make nickel a firm favourite in catalysis
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ResearchGiant ‘supersnowflakes’ start to lay
Self-assembled supramolecular structures overcome previous limitations
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ResearchProtein cation is strongest organic acid ever made
Even inert gases fall prey to highly charged proteins
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ResearchFullerene nanoflask captures reactivity of atomic nitrogen
‘Molecular surgery’ transforms fullerenes into nano-scale flasks
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