Cell reprogramming

Small molecules that switch up cell development could transform medicine

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Turning mature somatic cells back into flexible stem cells using small molecules could revolutionise medicine, especially for regeneration and cancer. Philip Ball reports

Z- and B-DNA

More than a mirror-image: left-handed nucleic acids

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Now a biological reality, researchers are starting to figure out the many roles of left-handed nucleic acids such as Z-DNA – from immunity to controlling our genetics. Rachel Brazil reports 

Polymer scrabble

Editing polymer backbones

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Changing the chemical makeup of a polymer backbone could revolutionise how we make, use and even recycle plastics. James Mitchell Crow reports

TB diagnosis

Testing times for tuberculosis

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Nina Notman takes a look at the recent and upcoming diagnostic and screening innovations aiming to drive down the incidence of tuberculosis globally

  • Marvellous mixtures of metals

  • The chemistry of love

  • An alternative approach to baking

  • The quantum dot story

  • Using DNA evidence to picture suspects

  • The drug developers fighting the antibiotic resistance problem

  • The liquid metals giving catalysis a new phase

More features

  • Cubane and benzene drugs

    Cubanes help drugs take the strain

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    Medicinal chemists are increasingly exploring strained ring systems, George Barsted reports, believing they can serve as replacements for conventional building blocks in pharmaceuticals

  • Wheat field

    Is modern food lower in nutrients?

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    Studies suggest that our fruit and vegetables are losing nutrients. Bárbara Pinho examines the evidence and looks at the implications of a ‘nutrient collapse’

  • Bonds under pressure

    When a bond gets too extreme

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    Chemical bonds are part of the way chemists rationalise the behaviour of atoms in the conditions of the world around them. Tim Wogan looks at how they are affected when those conditions change