Photocatalytic skeletal editing technique migrates substituents to challenging meta-position
Meta-substituted aromatic rings are key structures in many drug molecules
Sunlight-driven process upcycles polystyrene waste and elemental sulfur into valuable organic compounds
Products could be used as building blocks for semiconductor materials
Polytope formalism offers a new way to chart chemical space
Framework can investigate regions of chemical space that are normally inaccessible, painting a clearer picture of how molecules can form, transform and interconvert
First half-Möbius molecule made
Twisted structure is an unprecedented case of a compound that becomes aromatic by breaking its own symmetry
Unconventional catalyst support promotes record green methanol synthesis from carbon dioxide
New computer file could standardise how chemists report MOF syntheses
Quantum tunnelling harnessed to radically improve efficiency of separation of deuterium from water
Stable copper sandwich complexes complete the 3d transition-metal metallocene series
Citric acid cycle a ‘garbage compactor’ as well as an energy powerhouse
Radical chemistry pioneer Moses Gomberg probably made a trivalent carbon years before he realised
Highlights
Cone snail venom peptides offer new hope for pain relief
Cone snails deploy sophisticated venom cocktails to paralyse prey. Anthony King talks to the researchers harnessing these peptides to develop new pain medications
Unravelling the chemistry behind the sea’s bioluminescent sparkle
Researchers are piecing together the unusual chemical reactions that enable dinoflagellates to create spectacular light displays in tropical bays. But the mechanism behind their bioluminescence remains one of nature’s most puzzling chemical mysteries
Unlocking the power of plasma for chemistry
Scientists are using non-thermal plasma to produce fertiliser and long-chain hydrocarbons. Mason Wakley talks to the chemists harnessing the fourth state of matter
New separation methods aim to improve global rare earth supply
Rare earth elements are essential for modern technology, but their similar chemistry makes separation difficult and expensive. Now researchers are exploring new technologies to streamline processing and bring down costs.
How RNA reveals clues to life’s origins on Earth
The discovery of catalytic RNA transformed our understanding of life’s beginnings. Clare Sansom explores how the RNA world hypothesis bridges the gap between non-living chemistry and the first cells
Topics
The quest to understand where atoms end
Atomic size measurements like van der Waals and covalent radii are central to chemistry, but are they grounded in reality?
Mapping tool delivers quantitative visualisations of steric interactions
Technique uncovers subtle interactions that previous methods have missed
Google’s AlphaGenome wants to do for DNA what AlphaFold did for proteins
Model predicts effect of mutations on sequences up to 1 million base pairs in length and is adept at tackling complex non-coding regions
AI tool dramatically reduces computing power needed to find protein-binding molecules
Purer silicon lets robust quantum computing get started on a new medium
Anomeric effect cannot be explained by hyperconjugation alone
AI agents set to democratise computational chemistry
AI flexes its protein design muscles for harsh environments
Embodying polymer chemistry with a purpose by upcycling plastics and trapping PFAS
For Frank Leibfarth, focussing on reactivity and selectivity helps him bridge the gap between fundamental and applied research
Roman-era ink reveals surprising chemical complexity
2000-year-old residue indicates the Romans wrote with iron-gall inks hundreds of years earlier than expected
The chemist using curry to understand indoor air pollution
Ashish Kumar’s research reveals how cooking shapes the air we breathe indoors
Traditional yoghurt recipe reveals ants’ fermentation power
Rebecca Trager meets a cross-disciplinary team investigating an ancient way to make yoghurt, which involved a trip to a tiny Bulgarian village
Sunlight-driven process upcycles polystyrene waste and elemental sulfur into valuable organic compounds
Products could be used as building blocks for semiconductor materials
Green chemistry and sustainable manufacturing in India
Pathways, policies and the role of chemists in building a circular chemical economy
AAAS annual meeting & plasma chemistry
In this episode, we discuss reflections from this year’s AAAS annual meeting, the latest advances in plasma chemistry, and hear the latest headlines.
Rethinking hydrogen peroxide production
Hydro-Oxy and Addible both aim to transform how industry produces and uses a ubiquitous oxidant.
Textiles in the age of sustainability: alternative methods for fabric dyeing and treatment
Learn about advances in sustainability of textile production – join us on 31 March
Global analysis identifies trends in platform chemical research
Ammonia and methanol lead shift towards greener technologies
US researchers are advising students not to enter academia
A survey of NIH-grantees in Massachusetts reveals delayed hiring in labs, layoffs, careers being pursued abroad and research scope reductions
Two US states warned suspension of new tech visas for universities will hurt science
Move by Florida and Texas could be ‘devastating’ for research and other sectors experts warn amid concerns bans could spread
Chinese Academy of Sciences proposes capping pay-to-publish fees for high-profile journals
Journals charging article processing charges for open access in excess of $5000 are likely to be hit
Finding a home in the workshop
Departmental workshops provide support for researchers in more ways than one
AAAS annual meeting & plasma chemistry
In this episode, we discuss reflections from this year’s AAAS annual meeting, the latest advances in plasma chemistry, and hear the latest headlines.